Some of the most popular acne cream products today contain either antimicrobials or retinoids. Antimicrobials inhibit or kill acne causing bacteria. On the other hand, retinoids, derived from Vitamin A, unclog pores and stop the formation of whiteheads and blackheads. Following are examples of these.

Topical Antimicrobials

· Clindamycin is a semi-synthetic antibiotic. It reduces acne and lessens inflammation. Clindamycin has been proven to be safe and well tolerated. However, side effects such as irritation and skin dryness are possible. It can decrease the bacterial resistance that often occurs when antibiotics are used.

· Erythromycin’s properties are both anti inflammatory and antimicrobial. Acne cream preparations that combine erythromycin and benzoyl peroxide have been proven to be very effective. Side effects include dryness and irritation of the treated area. It also decreases bacterial resistance caused by using antibiotics.

Topical Retinoids

· Adapalene is a synthetic retinoid that unclogs pores and has moderate to potent anti-inflammatory properties. Minor skin irritation and dryness may occur with use.

· The first retinoid produced for topical (applied to skin) use was Tretinoin. Tretinoin is a natural retinoid which over time unclogs pores, and helps keep them unclogged. Redness, itching, and burning, are some of the side effects observed in users.

Topical Niacinamide (also called Nicotinamide)

After Vitamin-A derived retinoids, the most recent revolutionary treatment for acne comes from a substance called niacinamide. It is derived from niacin, a component of the Vitamin B complex.

In a New York University study, acne treatment and niacinamide was the subject, and 76 people were tested for the acne healing effects of 1% clindamycin gel compared to 4% Niacinamide gel. The preparations were used on moderate to inflammatory acne, twice daily for eight weeks.

The result – 82% of niacinamide patients showed improvement as compared to only 68% of clindamycin patients. Niacinamide is the preferred choice because it doesn’t diminish bacterial resistance, as Clindamycin is widely known for.

Niacinamide (sometimes called Nicotinamide) in cream or gel form is one of the most effective acne treatments available. Some advantages are…

· It is safe and natural to keep using it for as long as necessary.
· It will not make your skin develop bacterial resistance unlike most antimicrobials.
· It is ideal if you have dry, sensitive skin and cannot tolerate retinoids well.

Additionally, a 4% Niacinamide cream (such as Acnessential brand) can be applied alongside retinoids and antibiotics, or on its own.

Go visit for more information about topical niacinamide.

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